Harrah's and Ameristar both have nice poker rooms. Both of these casinos are located west of St. Louis in St. Louis and St. Charles Counties on the Missouri River. Be advised that Missouri has a $500 loss limit in place per "cruise". Every two hours players are allowed to buy in for up to $500. Many higher limit players will buy in near the end of the two hour period and then again at the beginning of the next two hour period.

The President casino is located in the city limits within walking distance of the Gateway Arch. It is a casino that is on its last legs evidenced by the dirtiness of the casino. It has a small poker room on the first floor.