The wife and I did this trip in April, from Cincinnati, to Tunica. We stayed at the Days Inn, which had shuttle service to any of the casino's.
From there we were going to Biloxi, but made a stop in New Orleans. The Harrah's there is Great.Overnight there we were off to Biloxi, with stops in Bay St.Louis, and Gulfport. Three days in Biloxi and we were off to Gulf Shores, Alabama. No casino's but one of the nicest beaches we've been to in a while. From there we spent a night in Nasville, then home. 2100 miles, and if I had my pick, I would be on a plane to Vegas!!!!*vbg* I'm still tired....